The Japanese Journal of Physiology
Print ISSN : 0021-521X
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Two-Week, but Not 1-Week, Hypoxic Exposure Enhances Nitric Oxide-Mediated Basal Tone Regulation in Rat Resistance Pulmonary Arteries
M. ShiraiA. ShimouchiS. IkedaH. OyaK.-Y. MinA. T. KawaguchiH. MoriI. Ninomiya
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2001 Volume 51 Issue 3 Pages 395-398

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Abstract

We measured internal diameter (ID) changes in resistance and conduit pulmonary arteries of 1- and 2-week hypoxic rats and normoxic control rats in response to nitric oxide synthase (NOS) inhibitors in vivo. At 2 weeks of hypoxic exposure, the ID reduction as a result of NOS inhibition was enhanced within the resistance arteries, but not at 1 week of hypoxia.

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© 2001 by The Physiological Society of Japan
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