Kansenshogaku Zasshi
Online ISSN : 1884-569X
Print ISSN : 0387-5911
ISSN-L : 0387-5911
Invasive Amebiasis at an Institution for the Mentally Retarded in Shizuoka Prefecture
Keiji SAHARAWataru HORITakashi MASUDAKatsuhiko OHATAFumie YAMAZAKISousuke AKAHANEHiroshi HATTORIHajimu YUASAIkko HASHIZUMEYuji TANAKAKouichi NAGAKURAHiroshi TACHIBANA
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1996 Volume 70 Issue 1 Pages 1-6

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Abstract

Amebiasis caused by Entamoeba histolytica at an institution for mentally retarded in Shizuoka Prefecture is reported. Five of the 50 patients showed E. histolytica cysts in their stools and 4 were positive serologically. The polymerase chain reaction and restriction fragment length polymorphism revealed that the isolates were pathogenic-type E. histolytica. Epidemiological analysis revealed that the amebic infection was caused by the abnormal behavior of mentally retarded patients. Administration of diloxanide furoate and metronidazole for cyst-carriers eliminated cysts from the stool and lowered the antibody titer.

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© The Japansese Association for Infectious Diseases
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