In the Tohoku-Pacific Ocean Earthquake, many onshore structures were destroyed by the tsunami, the wave height of which exceeded the conventional assumption. In the future, the reinforcement of tsunami disaster prevention measures will be needed, and the evaluation of inundation height and tsunami wave force on onshore structures will be important. In this study, two difference numerical analyses, two-dimensional nonlinear shallow water analysis and three-dimensional Navier-Stokes simulation that can reproduce the topography, building structures, the water depth were carried out for Tohoku Electric Power Haramachi thermal power station which suffered serious damage by tsunami caused by Tohoku-Pacific ocean earthquake. The run-up process of tsunami, inundation height of the main building and tsunami wave force on onshore structures were evaluated by comparison with the actual traces of the disaster, and the applicability of the three-dimensional simulation is examined for the evaluation of inundation height and tsunami wave force on onshore structures.