巻号一覧
後続誌
53 巻 (2009)
- 4 号 p. 99-
- 3 号 p. 49-
- 2 号 p. 17-
- 1 号 p. 1-
53 巻, 2 号
選択された号の論文の6件中1～6を表示しています
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シンポジウム：食物アレルギー研究の最前線
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池澤 善郎原稿種別: シンポジウム1：食物アレルギー研究の最前線
2009 年 53 巻 2 号 p. 17-23
発行日: 2009年
公開日: 2009/12/04
ジャーナル フリーIn this paper, at first the definition and epidemiology of food allergy, relationship between type of food allergy and the onset, and route of food sensitization were explained. Then, the pathomechanism of oral allergy syndrome (OAS) of IgE-mediated class 2 food allergy, late-onset natto anaphylaxis and enhancement effect of NSAIDs on food allergy were discussed as topics of recent food allergy.
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栗原 和幸原稿種別: シンポジウム1：食物アレルギー研究の最前線
2009 年 53 巻 2 号 p. 25-27
発行日: 2009年
公開日: 2009/12/04
ジャーナル フリーSpeaking of the current treatment of food allergy, the only way is the possible hope of outgrowing the food allergy while on allergen avoidance diet and education in case of accidental food ingestion. However, understanding the transcutaneous sensitization and oral immnunotolerance to food antigens, thorough innovation of our whole concept for the pathogenesis of food allergy may be required. Intentional oral intake of foods may be promising measure to prevent or cure food allergy.
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板垣 康治原稿種別: シンポジウム1：食物アレルギー研究の最前線
2009 年 53 巻 2 号 p. 29-31
発行日: 2009年
公開日: 2009/12/04
ジャーナル フリーA wide variety of foods cause allergy in sensitized subjects. In general, allergy-inducing substances (allergens) are proteins. Thus, hypoallergenic foods can be produced by removal, digestion or denaturation of allergens, in consideration of their own properties in various points such as heat-stability, digestibility, solubility, and conformation. The development of hypoallergenic-foods can contribute not only to the prevention of food allergy but also to the therapy of food allergy.
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松本 健治原稿種別: シンポジウム1：食物アレルギー研究の最前線
2009 年 53 巻 2 号 p. 33-35
発行日: 2009年
公開日: 2009/12/04
ジャーナル フリーIntestinal microbiota plays important roles in the immune development of the host, including the induction of oral tolerance. Recent studies have demonstrated that lactobacillus is critically involved in the development of allergic diseases in childhood. Recent meta-analysis has shown that prenatal and postnatal probiotic supplementation reduces prevalence of atopic dermatitis in the offspring but did not affect allergic sensitization or prevalences of other allergic diseases. The mechanisms how lactobacillus affects host immune responses remain largely unknown. The clinical importance of the effect of probiotics and the mechanisms involved require further investigation.
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山本（前田） 万里原稿種別: シンポジウム1：食物アレルギー研究の最前線
2009 年 53 巻 2 号 p. 37-40
発行日: 2009年
公開日: 2009/12/04
ジャーナル フリーO-Methylated (−)-epigallocatechin gallates (EGCGs) have an anti-allergic action, and the Japanese tea cultivar ‘Benifuuki’ is rich in EGCG3''Me, which is lost due to processing in black tea. Oral administration of O-methylated EGCGs significantly and dose-dependently inhibited type I allergic reactions in mice. O-methylated EGCGs also strongly inhibited mast cell activation through the prevention of tyrosine phosphorylation of cellular protein and high-affinity IgE receptor expression, as well as histamine/leukotriene release. Over a one-month period, drinking ‘Benifuuki’ green tea was useful to reduce some of the symptoms of Japanese cedar pollinosis, and did not affect any normal immune response in subjects with seasonal rhinitis. The AUC (area under the drug concentration time curve) of EGCG3''Me was 6.4 times that of EGCG in healthy human volunteers. Furthermore, many foods and household goods used ‘Benifuuki’ green tea were developed and sold by several manufacturers.
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短報
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横濱 道成, 佐山 勇輔, 小川 博原稿種別: 短 報
2009 年 53 巻 2 号 p. 41-42
発行日: 2009年
公開日: 2009/12/04
ジャーナル フリーTo prospect any value of animal resource of the emu as new domestic fowl, we analyzed albumen components in emu and nine other birds by SDS-polyacrylamide electrophoresis. The electrophoresis pattern of emu was quite different from that of chicken and other birds. Proteins with identical mobilities to chicken ovalbumin and lysozyme, major allergic proteins in chicken albumen, were not found in emu albumen. Emu egg could be promising as an alternative food for allergic patients against chicken albumen.
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