Diagnostic significance of tanned sheep erythrocyte electrophoretic mobility test (TEEM) was studied for gynecological malignancy.
Lymphocytes from gynecological malignancy and non-malignancy were obtained by differential centrifugation and incubated with encephalitogenic protein reported by Field and Caspary. Tanned sheep erythrocytes were added to the supernates and electrophoretic mobilities were measured in an analytical cell microelectrophoresis apparatus (Cytopherometer, Zeiss).
Decrease of the electrophoretic mobility was more significant in the supernate from malignancy than in that from non-malignancy. The substance which reduced electrophoretic mobility of erythrocytes also inhibited macrophage migration.
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