The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
NEW ANTIBIOTIC U-64846: FERMENTATION, ISOLATION AND CHARACTERIZATION
L. A. DOLAKT. M. CASTLEB. R. HANNONF. REUSSER
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1984 Volume 37 Issue 2 Pages 96-102

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Abstract

Antibiotic U-64846 is a new entity with the molecular formula C18H35ClN4O9 (MW 486). It is a very water soluble, reddish solid which decomposes above 300°C and which is air-sensitive. The antibiotic is produced by Streptomyces braegensis and it inhibits a variety of Gram-positive bacteria. Acidic hydrolysis gave 3, 7-diaminoheptanoic acid. The antibiotic gives 1H NMR, 13C NMR, IR and UV spectra which indicate it is not closely related to known antibiotic families.

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© Japan Antibiotics Research Association
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