Genetic Polymorphism of ADA in Taiwan Aboriginal Populations: New ADA Variants Detected by Isoelectric Focusing Method

FENG JIN; NARUYA SAITOU; TAKAFUMI ISHIDA; CHEIH-SHAN SUN; I-HUNG PAN; KEIICHI OMOTO; SATOSHI HORAI

doi:10.1537/ase.103.227

FENG JIN, NARUYA SAITOU, TAKAFUMI ISHIDA, CHEIH-SHAN SUN, I-HUNG PAN, KEIICHI OMOTO, SATOSHI HORAI

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Keywords: ADA variants, Gaoshan, Taiwan, IEF, genetic polymorphism

JOURNAL FREE ACCESS

1995 Volume 103 Issue 3 Pages 227-234

DOI https://doi.org/10.1537/ase.103.227

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Abstract

ADA subtype polymorphism in nine aboriginal populations (Gaoshan) of Taiwan was studied by means of the IEF method. A new ADA variant allele, ADA^*Taiwan1, was in a high allele frequency in two Gaoshan populations, the Amis and the Paiwans. Another new variant, ADA^*Taiwan2, was found in only one case of heterozygote in the Saisiats. Allele frequencies of a common allele, ADA^*2, in the Paiwans and the Amis were the highest among the Asian populations so far studied.

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