Identification and Characterization of a Gene Encoding an ABC Transporter Expressed in the Dicarboxylic Acid-Producing Yeast Candida maltosa

Yoshiyuki SAGEHASHI; Hiroyuki HORIUCHI; Ryouichi FUKUDA; Akinori OHTA

doi:10.1271/bbb.130595

Microbiology & Fermentation Technology Notes

Identification and Characterization of a Gene Encoding an ABC Transporter Expressed in the Dicarboxylic Acid-Producing Yeast Candida maltosa

Yoshiyuki SAGEHASHI, Hiroyuki HORIUCHI, Ryouichi FUKUDA, Akinori OHTA

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Keywords: Candida maltosa, n-alkane, dicarboxylic acid, ABC transporter

JOURNAL FREE ACCESS

2013 Volume 77 Issue 12 Pages 2502-2504

DOI https://doi.org/10.1271/bbb.130595

View "Advance Publication" version (December 7, 2013).

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Abstract

A gene, CmCDR1, encoding an ABC transporter of the dicarboxylic acid (DCA)-producing yeast Candida maltosa was cloned. Transcription of CmCDR1 was upregulated in a DCA-hyper-producing mutant of C. maltosa in a later phase of culture on n-dodecane, but not in its parental strain. CmCDR1 expression was significantly induced by the longer-chain DCA in this mutant.

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