The Journal of Biochemistry
Online ISSN : 1756-2651
Print ISSN : 0021-924X
Identification of a New Imprinted Gene, Rian, on Mouse Chromosome 12 by Fluorescent Differential Display Screening
Izuho HatadaSumiyo MoritaYayoi ObataYusuke SotomaruMasafumi ShimodaTomohiro Kono
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2001 Volume 130 Issue 2 Pages 187-190

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Abstract

Systematic screening of differentially expressed genes among androgenetic, partheno-genetic, and normal embryos by means of fluorescent differential display revealed five imprinted genes. One of them, named Rian, was expressed exclusively from the maternal allele and was closely linked to an imprinted gene, Meg3(Gt12), mapped to the distal end of chromosome 12. The Rian transcript did not have any apparent open reading frame, and its transcript was exclusively localized to the nucleus.

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© The Japanese Biochemical Society
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