BioScience Trends
Online ISSN : 1881-7823
Print ISSN : 1881-7815
ISSN-L : 1881-7815
Reviews
Traditional Chinese medicine for human papillomavirus (HPV) infections: A systematic review
Jing Lin, Lanting Chen, Xuemin Qiu, Na Zhang, Qiting Guo, Yan Wang, Mingyan Wang, Hans-Jürgen Gober, Dajin Li, Ling Wang
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Keywords: Traditional Chinese medicine, human papillomavirus (HPV), HPV infection, cervical cancer, genital warts
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2017 Volume 11 Issue 3 Pages 267-273

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Abstract

Human papillomavirus (HPV) infections are common and generally harmless, but persistent infections can bring health problems like cancer and genital warts. For the uninfected group, HPV vaccines provide safe and effective protection, but they're type-restricted and expensive. For those infected, so far there have been a handful of treatments for HPV-associated benign or malignant diseases, traditional Chinese medicine being one of them. This systematic review focuses on the application of traditional Chinese medicine in HPV infection and related diseases on the basis of clinical findings. Moreover it covers compositions and mechanisms based on in vitro laboratory methods and animal models. Traditional Chinese medicine improves clinical index in the treatment of cervical cancer and genital warts; the mechanisms behind the effectiveness might be the regulation of cell apoptosis, viral gene transcription and translation, cell signal transduction pathways, and immune function.

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© 2017 International Research and Cooperation Association for Bio & Socio-Sciences Advancement
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