Differentiation Between Patients With Takotsubo Cardiomyopathy and Those With Anterior Acute Myocardial Infarction

Masaru Inoue; Masami Shimizu; Hidekazu Ino; Masato Yamaguchi; Hidenobu Terai; Noboru Fujino; Kenji Sakata; Akira Funada; Ryozo Tatami; Syozo Ishise; Hounin Kanaya; Hiroshi Mabuchi

doi:10.1253/circj.69.89

Clinical Investigation

Differentiation Between Patients With Takotsubo Cardiomyopathy and Those With Anterior Acute Myocardial Infarction

Masaru Inoue, Masami Shimizu, Hidekazu Ino, Masato Yamaguchi, Hidenobu Terai, Noboru Fujino, Kenji Sakata, Akira Funada, Ryozo Tatami, Syozo Ishise, Hounin Kanaya, Hiroshi Mabuchi

Author information

Masaru Inoue
Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University
Masami Shimizu
Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University
Hidekazu Ino
Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University
Masato Yamaguchi
Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University
Hidenobu Terai
Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University
Noboru Fujino
Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University
Kenji Sakata
Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University
Akira Funada
Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University
Ryozo Tatami
Division of Cardiology, Maizuru Kyousai Hospital
Syozo Ishise
Division of Cardiology, Maizuru Kyousai Hospital
Hounin Kanaya
Division of Cardiology, Ishikawa Prefectural Hospital
Hiroshi Mabuchi
Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University

Keywords: Anterior myocardial infarction, Electrocardiogram, Takotsubo cardiomyopathy, Transient left ventricular apical ballooning

JOURNAL FREE ACCESS

2005 Volume 69 Issue 1 Pages 89-94

DOI https://doi.org/10.1253/circj.69.89

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Abstract

Background There has not been a comparison of the electrocardiographic (ECG) finding of ST-segment elevation in the precordial leads in patients with takotsubo cardiomyopathy (TC) and those with anterior acute myocardial infarction (AMI), with regard to the location of the culprit lesion. Methods and Results The present study evaluated 18 patients with TC, and 85 with anterior AMI who were divided into 3 groups: group A had the culprit lesion proximal to both the first septal branch (S1) and the first diagonal branch (D1), group B had the culprit lesion proximal to either S1 or D1, and group C had the culprit lesion distal to both S1 and D1. In patients with TC, reciprocal ST-segment depression in the inferior leads was observed less frequently than in patients in groups A (p<0.0001) and B (p=0.0002), and abnormal Q waves and ST-segment elevation in the inferior leads were observed more frequently than in group A (p=0.0007, p=0.0057, respectively). The ECG findings in TC did not differ from those in group C. Conclusion Electrocardiographic findings may differentiate TC from AMI with a proximal lesion of left anterior descending coronary artery, but not those with distal lesions. (Circ J 2005; 69: 89 - 94)

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