Deteriorative Effect of Smoking on Target Lesion Revascularization After Implantation of Coronary Stents With Diameter of 3.0 mm or Less

Tetsuya Ishikawa; Hidenori Yagi; Takashi Ogawa; Chikara Mori; Hiroshi Takeda; Hiroshi Sakamoto; Makoto Mutoh; Atsushi Seo; Takahiro Shibata; Satoru Yoshida; Kamon Imai; Toshinobu Horie; Seibu Mochizuki

doi:10.1253/circj.69.227

Clinical Investigation

Deteriorative Effect of Smoking on Target Lesion Revascularization After Implantation of Coronary Stents With Diameter of 3.0 mm or Less

Tetsuya Ishikawa, Hidenori Yagi, Takashi Ogawa, Chikara Mori, Hiroshi Takeda, Hiroshi Sakamoto, Makoto Mutoh, Atsushi Seo, Takahiro Shibata, Satoru Yoshida, Kamon Imai, Toshinobu Horie, Seibu Mochizuki

Author information

Tetsuya Ishikawa
Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kohnan
Hidenori Yagi
Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine
Takashi Ogawa
Division of Cardiology, Fuji City Central Hospital, Fuji
Chikara Mori
Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine
Hiroshi Takeda
Division of Cardiology, Fuji City Central Hospital, Fuji
Hiroshi Sakamoto
Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kohnan
Makoto Mutoh
Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kohnan
Atsushi Seo
Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine
Takahiro Shibata
Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine
Satoru Yoshida
Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine
Kamon Imai
Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kohnan
Toshinobu Horie
Division of Cardiology, Saitama Cardiovascular and Respiratory Center, Kohnan
Seibu Mochizuki
Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine

Keywords: Percutaneous coronary intervention (PCI), Restenosis, Smoking, Target lesion revascularization (TLR)

JOURNAL FREE ACCESS

2005 Volume 69 Issue 2 Pages 227-231

DOI https://doi.org/10.1253/circj.69.227

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Abstract

Background Although smoking cessation is widely encouraged because of the associated risk of cardiovascular events, the impact of smoking on target lesion revascularization (TLR) after percutaneous coronary intervention (PCI) is controversial. Therefore, the present study retrospectively investigated the effect of smoking on TLR after plain-old balloon angioplasty (POBA; n=376) and stenting (STENT; n=434) in patients undergoing secondary coronary angiography at a single center. Methods and Results A smoker was defined as current smoking or quitting within 2 years of the first PCI. In the POBA group, the predictors for TLR, as calculated by multiple logistic regression analysis, were a complex type of lesion (p<0.0001) and the left anterior descending artery (LAD) as affected vessel (p<0.05). In the STENT group, the predictors were the final % diameter of stenosis after stenting, measured by quantitative coronary arteriography (p<0.0005), LAD (p<0.01), and smoking (p=0.049). When the STENT group was divided into 2 groups according to the diameter of the implanted stent, smoking was a predictive factors for TLR in the group that received relatively small stents (diameter ≤3.0 mm) (p<0.02), but not in the group that received larger stents (diameter ≥3.5 mm). Conclusion Smoking has a deteriorative effect on TLR after implantation of relatively small coronary stents with a diameter of 3.0 mm or less. (Circ J 2005; 69: 227 - 231)

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