Importance of Dual Induction Tests for Coronary Vasospasm and Ventricular Fibrillation in Patients Surviving Out-of-Hospital Cardiac Arrest

Yusuke Takagi; Satoshi Yasuda; Jun Takahashi; Morihiko Takeda; Masaharu Nakayama; Kenta Ito; Masanori Hirose; Yuji Wakayama; Koji Fukuda; Hiroaki Shimokawa

doi:10.1253/circj.CJ-09-0061

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Importance of Dual Induction Tests for Coronary Vasospasm and Ventricular Fibrillation in Patients Surviving Out-of-Hospital Cardiac Arrest

Yusuke Takagi, Satoshi Yasuda, Jun Takahashi, Morihiko Takeda, Masaharu Nakayama, Kenta Ito, Masanori Hirose, Yuji Wakayama, Koji Fukuda, Hiroaki Shimokawa

Author information

Yusuke Takagi
Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
Satoshi Yasuda
Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
Jun Takahashi
Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
Morihiko Takeda
Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
Masaharu Nakayama
Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
Kenta Ito
Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
Masanori Hirose
Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
Yuji Wakayama
Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
Koji Fukuda
Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
Hiroaki Shimokawa
Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine

Keywords: Coronary vasospasm, Electrophysiology, Sudden cardiac death

JOURNAL FREE ACCESS

2009 Volume 73 Issue 4 Pages 767-769

DOI https://doi.org/10.1253/circj.CJ-09-0061

View "Advance Publication" version (March 3, 2009).

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Abstract

Background: The pathogenesis of out-of-hospital cardiac arrest (OHCA) without organic heart disease has not been fully investigated. Methods and Results: Induction tests were performed in 12 consecutive patients with OHCA for both coronary vasospasm with intracoronary acetylcholine and ventricular fibrillation (VF) with programmed stimulation at 1 month after the event. All patients were positive for 1 of the tests: coronary vasospasm alone in 3, VF alone in 2, and both in 7. All patients underwent implantable cardioverter defibrillator (ICD) implantation and appropriate ICD shock was documented in 1 patient. Conclusions: OHCA has a heterogeneous pathogenesis and so dual induction tests are necessary. (Circ J 2009; 73: 767 - 769)

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