Synthetic Approaches toward Ecteinascidins. Part 2. Preparation of the ABCDE Ring System of Ecteinascidins Having Characteristic Substituents in Both Benzene Rings

Naoki Saito; Ryu-ichi Seki; Noriko Kameyama; Rie Sugimoto; Akinori Kubo

doi:10.1248/cpb.51.821

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Synthetic Approaches toward Ecteinascidins. Part 2.
Preparation of the ABCDE Ring System of Ecteinascidins Having Characteristic Substituents in Both Benzene Rings

Naoki Saito, Ryu-ichi Seki, Noriko Kameyama, Rie Sugimoto, Akinori Kubo

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Keywords: ecteinascidin, marine natural product, synthesis, pentacyclic framework, protected phenol

JOURNAL FREE ACCESS

2003 Volume 51 Issue 7 Pages 821-831

DOI https://doi.org/10.1248/cpb.51.821

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Abstract

A synthesis of an advanced ABCDE ring system (24c) having characteristic substituents in both benzene rings of ecteinascidin marine natural products is described based on our model studies.

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