Notes
Four Novel Metabolites from Microbial Transformation of Curcumol by Cunninghamella blakesleana
2007 Volume 55 Issue 3 Pages 451-454
Details
2007 Volume 55 Issue 3 Pages 451-454
Further study on the microbial transformation of curcumol (1) by Cunninghamella blakesleana (AS3.970) led to the isolation of four novel metabolites. Their structures were elucidated as 3β-hydroxy curcumol (2), 12-hydroxy curcumol (3), 1α-hydroxy-10β,14-epoxy curcumol (4) and (2S,4S,5S,7S)-10-hydroxymethyl-7-isopropyl-2-methoxy-4-methyl-1-oxaspiro[4,6]undec-10-en-8-one (5) on the basis of spectral methods. All of them were characterized as new compounds.
