Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
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Paralemnolins J—P, New Sesquiterpenoids from the Soft Coral Paralemnalia thyrsoide
Guey-Horng WangHo-Cheng HuangJui-Hsin SuYang-Chang WuJyh-Horng Sheu
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2010 Volume 58 Issue 1 Pages 30-33

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Abstract

Six new sesquiterpenoids, paralemnolins J—O (1—6), along with one novel norsesquiterpenoid, paralemnolin P (7), have been isolated from the soft coral Paralemnalia thyrsoides. The structures of metabolites 1—7 were established on the basis of extensive NMR study and chemical methods. The structure of 5 was further confirmed by a single-crystal X-ray analysis. Cytotoxicity of these metabolites toward a limited panel of cancer cell lines also is described.

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© 2010 The Pharmaceutical Society of Japan
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