Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Pyrrolo [1', 2' : 1, 2] pyrazino [6, 5-c] carbazoles. Synthese et Etude des Spectres de Resonnance Magnetique Nucleaire
JEAN-CHARLES LANCELOTJEAN-MARIE GAZENGELSYLVAIN RAULTMAX ROBBA
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Keywords: ^1H NMR
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1982 Volume 30 Issue 5 Pages 1674-1679

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Abstract

Synthesis of pyrrolo [1', 2' : 1, 2] pyrazino [6, 5-c] carbazole derivatives is described starting from 3-amino-4, 6-dinitro-9-ethylcarbazole (1). The pyrrole ring is obtained by reaction with 2, 5-dimethoxytetrahydrofuran. Cyclization of the pyrazine ring is achieved after reduction of the nitro grouping by intramolecular cyclization of 4, 6-diamino-9-ethyl-3-(1-pyrrolyl) carbazole derivatives. 1H nuclear magnetic resonance spectra are studied.

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© The Pharmaceutical Society of Japan
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