REVIEW
Vasa Homolog Genes in Mammalian Germ Cell Development
2001 Volume 26 Issue 3 Pages 131-136
Details
2001 Volume 26 Issue 3 Pages 131-136
Many vasa homologue genes to Drosophila vasa have been isolated in various animal species. They provide specific molecular probes to analyze the establishment and the differentiation of germ cell lineage. In mammals, the expression of VASA protein becomes detectable in PGCs at the late migrating stage. Interestingly, during spermatogenesis the intracellular localization of VASA protein is closely associated with the chromatoid body.
