リポソームの粒子設計による経口、経肺および点眼投与DDS製剤設計

小野寺 理沙子; 田原 耕平; 竹内 洋文

doi:10.2745/dds.30.121

[Feature articles] “Recent progress in pharmaceutical technologies for particulate drug delivery systems” Editor:Hideki Ichikawa

Advanced particle design of liposomes for drug delivery in oral, pulmonary and ocular administration

Risako Onodera, Kohei Tahara, Hirofumi Takeuchi

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Keywords: liposome, drug delivery, oral, pulmonary, ocular

JOURNAL FREE ACCESS

2015 Volume 30 Issue 2 Pages 121-128

DOI https://doi.org/10.2745/dds.30.121

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Abstract

Colloidal drug carriers such as liposomes, lipid emulsions, and polymeric nanoparticles have great potential to deliver drugs effectively. This article demonstrates recent our successful results in drug delivery using liposomal systems, mainly by oral, pulmonary and ocular routes. Especially, particle design, including modification of the liposomal surface with polymers, is a key to drug delivery with these systems.

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