Aggressive Thyroid Carcinoma Showing Thymic-Like Differentiation (Castle): Case Report and Review of the Literature

Carlo CAPPELLI; Andrea TIRONI; Gian Pietro MARCHETTI; Ilenia PIROLA; Elvira De MARTINO; Andrea DELBARBA; Maurizio CASTELLANO; Enrico Agabiti ROSEI

doi:10.1507/endocrj.K07E-147

ORIGINALS

Aggressive Thyroid Carcinoma Showing Thymic-Like Differentiation (Castle): Case Report and Review of the Literature

Carlo CAPPELLI, Andrea TIRONI, Gian Pietro MARCHETTI, Ilenia PIROLA, Elvira De MARTINO, Andrea DELBARBA, Maurizio CASTELLANO, Enrico Agabiti ROSEI

Author information

Carlo CAPPELLI
Department of Medical and Surgical Sciences, Internal Medicine and Endocrinology Unit, University of Brescia
Andrea TIRONI
II Pathological anatomy, University of Brescia
Gian Pietro MARCHETTI
Pulmonology Unit, Spedali Civili, Brescia
Ilenia PIROLA
Department of Medical and Surgical Sciences, Internal Medicine and Endocrinology Unit, University of Brescia
Elvira De MARTINO
Department of Medical and Surgical Sciences, Internal Medicine and Endocrinology Unit, University of Brescia
Andrea DELBARBA
Department of Medical and Surgical Sciences, Internal Medicine and Endocrinology Unit, University of Brescia
Maurizio CASTELLANO
Department of Medical and Surgical Sciences, Internal Medicine and Endocrinology Unit, University of Brescia
Enrico Agabiti ROSEI
Department of Medical and Surgical Sciences, Internal Medicine and Endocrinology Unit, University of Brescia

Keywords: Thyroid cancer, Carcinoma showing thymic-like differentiation, Castle

JOURNAL FREE ACCESS

2008 Volume 55 Issue 4 Pages 685-690

DOI https://doi.org/10.1507/endocrj.K07E-147

View "Advance Publication" version (June 18, 2008).

Details

Abstract

Carcinoma showing thymic-like differentiation (CASTLE) is a rare tumour of the thyroid, which arises from ectopic thymic tissue or remnants of branchial pouches. A systematic review of English literature evidences less than thirty cases; from them, it clearly appears that CASTLE is considered an indolent slow-growing neoplasia even when lymph nodes metastasis are present. We describe a case of very aggressive CASTLE, which showed seeding along fine needle aspiration tract.

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