Simultaneous Bilateral Spontaneous Pneumothorax Observed during the Administration of Gefitinib for Lung Adenocarcinoma with Multiple Lung Metastases

Masahide MORI; Masaru NAKAGAWA; Takeya FUJIKAWA; Takeo IWASAKI; Tomoko KAWAMURA; Yoshinobu NAMBA; Manabu NIINAKA; Yoshito TAKEDA; Hiromi KIMURA; Nobuyuki NAKA; Tatsuya OKADA; Toshihiko YAMAGUCHI; Soichiro YOKOTA; Masami ITO

doi:10.2169/internalmedicine.44.862

CASE REPORTS

Simultaneous Bilateral Spontaneous Pneumothorax Observed during the Administration of Gefitinib for Lung Adenocarcinoma with Multiple Lung Metastases

Masahide MORI, Masaru NAKAGAWA, Takeya FUJIKAWA, Takeo IWASAKI, Tomoko KAWAMURA, Yoshinobu NAMBA, Manabu NIINAKA, Yoshito TAKEDA, Hiromi KIMURA, Nobuyuki NAKA, Tatsuya OKADA, Toshihiko YAMAGUCHI, Soichiro YOKOTA, Masami ITO

Author information

Masahide MORI
Department of Respiratory Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka
Masaru NAKAGAWA
Department of Respiratory Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka
Takeya FUJIKAWA
Department of Respiratory Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka
Takeo IWASAKI
Department of Respiratory Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka
Tomoko KAWAMURA
Department of Respiratory Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka
Yoshinobu NAMBA
Department of Respiratory Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka
Manabu NIINAKA
Department of Respiratory Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka
Yoshito TAKEDA
Department of Respiratory Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka
Hiromi KIMURA
Department of Respiratory Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka
Nobuyuki NAKA
Department of Respiratory Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka
Tatsuya OKADA
Department of Respiratory Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka
Toshihiko YAMAGUCHI
Department of Respiratory Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka
Soichiro YOKOTA
Department of Respiratory Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka
Masami ITO
Department of Respiratory Medicine, National Hospital Organization Toneyama National Hospital, Toyonaka

Keywords: lung cancer, lung metastases, pneumothorax, chemotherapy, gefitinib

JOURNAL OPEN ACCESS

2005 Volume 44 Issue 8 Pages 862-864

DOI https://doi.org/10.2169/internalmedicine.44.862

Details

Abstract

A 41-year-old man with productive cough was admitted to our hospital. His chest roentgenogram showed multiple small nodules in the bilateral lung fields. The nodules were revealed as intrapulmonary metastases of the adenocarcinoma of the lung. Systemic chemotherapy with paclitaxel and carboplatin was not effective, and continuous oral gefitinib therapy was initiated. Twenty-one days later, spontaneous pneumothorax was found in the left lung, and four days after that, in the right lung as well. The extent of the pneumothorax was slight; therefore, he recovered without drainage within several days. Spontaneous pneumothorax, especially bilateral pneumothorax, is a rare complication of chemotherapy for lung cancer.

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