Subacute Thrombosis after Coronary Stenting Occurring with Resistance to Ticlopidine

Shunichiro Fuchigami; Shuichi Oshima; Seiji Hokimoto; Katsuo Noda; Hironobu Fukushima; Toshiaki Yoshida; Yukiko Takushi; Hisao Ogawa

doi:10.2169/internalmedicine.45.1438

CASE REPORTS

Subacute Thrombosis after Coronary Stenting Occurring with Resistance to Ticlopidine

Shunichiro Fuchigami, Shuichi Oshima, Seiji Hokimoto, Katsuo Noda, Hironobu Fukushima, Toshiaki Yoshida, Yukiko Takushi, Hisao Ogawa

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Keywords: subacute stent thrombosis after coronary stenting, ticlopidine resistance, platelet aggregation

JOURNAL OPEN ACCESS

2006 Volume 45 Issue 10 Pages 675-678

DOI https://doi.org/10.2169/internalmedicine.45.1438

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Abstract

A 79-year-old man underwent stent implantation from the proximal site to the left main trunk with one bare metal stent after rotation atherectomy. He received 200 mg/day ticlopidine and 200 mg/day aspirin from 2 days pre-stenting. Subacute thrombosis occurred 5 days after coronary stenting. We performed a test of platelet aggregation one month after the commencement of dual antiplatelet therapy and the test showed no response to ticlopidine in this case. An increased dose of ticlopidine was not effective for suppressing platelet aggregation. We report a case of subacute stent thrombosis which is related to ticlopidine resistance.

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