Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Adenovirus Fulminant Hepatic Failure: Disseminated Adenovirus Disease after Unrelated Allogeneic Stem Cell Transplantation for Acute Lymphoblastic Leukemia
Hideyuki Nakazawa, Toshiro Ito, Hideki Makishima, Noriko Misawa, Wataru Okiyama, Takeshi Uehara, Eiko Hidaka, Kendo Kiyosawa, Fumihiro Ishida
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Keywords: disseminated adenovirus disease, fulminant hepatic failure, bone marrow transplantation, leukemia
JOURNAL OPEN ACCESS

2006 Volume 45 Issue 16 Pages 975-980

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Abstract

Adenovirus is one of the major causes of non-relapse morbidity and mortality after allogeneic hematopoietic stem cell transplantation for hematological malignancy. Fulminant hepatic failure is a rare manifestation of post-transplant complication with adenovirus. Extremely high mortality and aggressiveness of the clinical course have been posing clinical challenges for the diagnosis as well as for the treatment. Here, we report a case with disseminated adenovirus disease presenting with fulminant hepatic failure after bone marrow transplantation for acute lymphoblastic leukemia.

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© 2006 by The Japanese Society of Internal Medicine
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