Membraneous Glomerulonephritis and Non-Hodgkin's Lymphoma in a Patient with Primary Sjögren's Syndrome

Nozomi Iwanaga; Makoto Kamachi; Keita Fujikawa; Toshiyuki Aramaki; Yasumori Izumi; Kazuhiko Arima; Mami Tamai; Kouichiro Aratake; Hideki Nakamura; Tomoki Origuchi; Hiroaki Ida; Atsushi Kawakami; Takashi Taguchi; Katsumi Eguchi

doi:10.2169/internalmedicine.46.1835

CASE REPORTS

Membraneous Glomerulonephritis and Non-Hodgkin's Lymphoma in a Patient with Primary Sjögren's Syndrome

Nozomi Iwanaga, Makoto Kamachi, Keita Fujikawa, Toshiyuki Aramaki, Yasumori Izumi, Kazuhiko Arima, Mami Tamai, Kouichiro Aratake, Hideki Nakamura, Tomoki Origuchi, Hiroaki Ida, Atsushi Kawakami, Takashi Taguchi, Katsumi Eguchi

Author information

Nozomi Iwanaga
First Department of Internal Medicine, Graduate School of Biomedical Sciences, Nagasaki, University, Nagasaki
Makoto Kamachi
First Department of Internal Medicine, Graduate School of Biomedical Sciences, Nagasaki, University, Nagasaki
Keita Fujikawa
First Department of Internal Medicine, Graduate School of Biomedical Sciences, Nagasaki, University, Nagasaki
Toshiyuki Aramaki
First Department of Internal Medicine, Graduate School of Biomedical Sciences, Nagasaki, University, Nagasaki
Yasumori Izumi
First Department of Internal Medicine, Graduate School of Biomedical Sciences, Nagasaki, University, Nagasaki
Kazuhiko Arima
First Department of Internal Medicine, Graduate School of Biomedical Sciences, Nagasaki, University, Nagasaki
Mami Tamai
First Department of Internal Medicine, Graduate School of Biomedical Sciences, Nagasaki, University, Nagasaki
Kouichiro Aratake
First Department of Internal Medicine, Graduate School of Biomedical Sciences, Nagasaki, University, Nagasaki
Hideki Nakamura
First Department of Internal Medicine, Graduate School of Biomedical Sciences, Nagasaki, University, Nagasaki
Tomoki Origuchi
Nagasaki University of Health Sciences, Nagasaki
Hiroaki Ida
First Department of Internal Medicine, Graduate School of Biomedical Sciences, Nagasaki, University, Nagasaki
Atsushi Kawakami
First Department of Internal Medicine, Graduate School of Biomedical Sciences, Nagasaki, University, Nagasaki
Takashi Taguchi
Second Department of Pathology, Nagasaki University School of Medicine, Nagasaki
Katsumi Eguchi
First Department of Internal Medicine, Graduate School of Biomedical Sciences, Nagasaki, University, Nagasaki

Keywords: Sjögren's syndrome, membraneous glomerulonephritis, lymphoma

JOURNAL OPEN ACCESS

2007 Volume 46 Issue 4 Pages 191-194

DOI https://doi.org/10.2169/internalmedicine.46.1835

Details

Abstract

The most common renal manifestation of Sjögren's syndrome is tubulointerstitial nephritis, and glomerular disease is rare (3). A 62-year-old woman with primary Sjögren's syndrome developed nephrotic syndrome. Kidney biopsy was consistent with membraneous glomerulonephritis. Steroid pulse therapy was not effective. Three months later she was diagnosed with non-Hodgkin's lymphoma of the tongue, and she was given CHOP therapy and radiation. Both the lymphoma and membraneous glomerulonephritis were resolved.

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