Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Membranous Nephropathy and Kimura's Disease Manifesting a Hip Mass. A Case Report with Literature Review
Yoko Obata, Akira Furusu, Tomoya Nishino, Hiroshi Ichinose, Aki Ohnita, Keisuke Iwasaki, Takashi Taguchi, Shigeru Kohno
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Keywords: membranous nephropathy, Kimura's disease, eosinophilia, hip mass
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2010 Volume 49 Issue 14 Pages 1405-1409

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Abstract

We report a case of Kimura's disease with membranous nephropathy. A 15-year-old Japanese boy was referred to our hospital with proteinuria and a subcutaneous mass in the hip. Renal biopsy demonstrated secondary membranous nephropathy (MN) with mild mesangial proliferation and some electron-dense deposits in the mesangium. Laboratory tests revealed eosinophilia and a high level of serum IgE, which are common findings in Kimura's disease. A biopsy of the mass in the hip was performed and Kimura's disease was diagnosed. Treatment with oral prednisolone resulted in a decrease of proteinuria and regression of the subcutaneous mass. Kimura's disease should be included in the differential diagnosis of secondary MN.

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© 2010 by The Japanese Society of Internal Medicine
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