Evaluation of the Effects of Exenatide Administration in Patients with Type 2 Diabetes with Worsened Glycemic Control Caused by Glucocorticoid Therapy

Koji Matsuo; Takuo Nambu; Yuki Matsuda; Yugo Kanai; Shin Yonemitsu; Seiji Muro; Shogo Oki

doi:10.2169/internalmedicine.52.8622

CASE REPORTS

Evaluation of the Effects of Exenatide Administration in Patients with Type 2 Diabetes with Worsened Glycemic Control Caused by Glucocorticoid Therapy

Koji Matsuo, Takuo Nambu, Yuki Matsuda, Yugo Kanai, Shin Yonemitsu, Seiji Muro, Shogo Oki

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Keywords: diabetes mellitus, glucocorticoids, incretin

JOURNAL OPEN ACCESS

2013 Volume 52 Issue 1 Pages 89-95

DOI https://doi.org/10.2169/internalmedicine.52.8622

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Abstract

Glucocorticoid-induced hyperglycemia is common in patients with or without known diabetes mellitus. Exenatide, a glucagon-like peptide-1 receptor agonist, improves glycemic control without causing weight gain or hypoglycemia and is currently widely used in patients with type 2 diabetes mellitus. We herein report four cases of patients with type 2 diabetes with worsened glycemic control due to glucocorticoids who were successfully treated with exenatide administration.

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