Snoring is Associated with an Impaired Motor Function, Disease Severity and the Quality of Life but not with Excessive Daytime Sleepiness in Patients with Parkinson's Disease

Keisuke Suzuki; Masayuki Miyamoto; Tomoyuki Miyamoto; Shiho Suzuki; Yuka Watanabe; Ayaka Numao; Masaoki Iwanami; Muneto Tatsumoto; Tsubasa Sada; Taro Kadowaki; Kenichi Hashimoto; Hideki Sakuta; Koichi Hirata

doi:10.2169/internalmedicine.52.9083

ORIGINAL ARTICLES

Snoring is Associated with an Impaired Motor Function, Disease Severity and the Quality of Life but not with Excessive Daytime Sleepiness in Patients with Parkinson's Disease

Keisuke Suzuki, Masayuki Miyamoto, Tomoyuki Miyamoto, Shiho Suzuki, Yuka Watanabe, Ayaka Numao, Masaoki Iwanami, Muneto Tatsumoto, Tsubasa Sada, Taro Kadowaki, Kenichi Hashimoto, Hideki Sakuta, Koichi Hirata

Author information

Keisuke Suzuki
Department of Neurology, Dokkyo Medical University, Japan
Masayuki Miyamoto
Department of Neurology, Dokkyo Medical University, Japan
Tomoyuki Miyamoto
Department of Neurology, Dokkyo Medical University Koshigaya Hospital, Japan
Shiho Suzuki
Department of Neurology, Dokkyo Medical University, Japan
Yuka Watanabe
Department of Neurology, Dokkyo Medical University, Japan
Ayaka Numao
Department of Neurology, Dokkyo Medical University, Japan
Masaoki Iwanami
Department of Neurology, Dokkyo Medical University Koshigaya Hospital, Japan
Muneto Tatsumoto
Department of Neurology, Dokkyo Medical University, Japan
Tsubasa Sada
Department of Neurology, Dokkyo Medical University, Japan
Taro Kadowaki
Department of Neurology, Dokkyo Medical University, Japan
Kenichi Hashimoto
Department of Neurology, Dokkyo Medical University, Japan
Hideki Sakuta
Department of Neurology, Dokkyo Medical University, Japan
Koichi Hirata
Department of Neurology, Dokkyo Medical University, Japan

Keywords: Parkinson's disease, snoring, excessive daytime sleepiness, quality of life, disease severity

JOURNAL OPEN ACCESS
Supplementary material

2013 Volume 52 Issue 8 Pages 863-869

DOI https://doi.org/10.2169/internalmedicine.52.9083

Details

Abstract

Objective There are conflicting results regarding the frequency and clinical significance of sleep related breathing disorders in patients with Parkinson's disease (PD). The aim of this study was to investigate the relationship between snoring and its clinical correlates in patients with PD.
Methods A total of 93 PD patients and 93 controls were analyzed from a previously conducted cross-sectional study. Snoring was defined as a snoring frequency of ≥2 days/week (a score of 2 or higher on the PD Sleep Scale-2 subitem 15). Excessive daytime sleepiness (EDS) was defined as an Epworth Sleepiness Scale score of ≥10.
Results Snoring was more prevalent in the patients with PD than in the controls (14.0% vs. 1.1%). The PD patients who snored exhibited greater disease severity, worse scores on the motor section of the Unified Parkinson's Disease Rating Scale (UPDRS) and the Parkinson fatigue scale and more impaired scores in several domains of the Parkinson's Disease Questionnaire, including the domains of mobility, activities of daily living, emotional well-being, communication and bodily discomfort, when compared to those who did not snore. No between-group differences were found in EDS. A higher proportion of the UPDRS motor scores for bradykinesia was seen in the PD patients who snored compared to that observed in the PD patients who did not snore.
Conclusion We found that snoring was more frequent in PD patients than in controls. Furthermore, snoring in PD patients was associated with disease severity, an impaired motor function and a decreased quality of life, although it was not associated with EDS.

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