Localized IgG4-related Cholecystitis Mimicking Gallbladder Cancer

Tadahisa Inoue; Fumihiro Okumura; Takashi Mizushima; Hirotada Nishie; Hiroyasu Iwasaki; Kaiki Anbe; Takanori Ozeki; Kenta Kachi; Shigeki Fukusada; Yuta Suzuki; Kazuko Watanabe; Hitoshi Sano

doi:10.2169/internalmedicine.54.4383

CASE REPORTS

Localized IgG4-related Cholecystitis Mimicking Gallbladder Cancer

Tadahisa Inoue, Fumihiro Okumura, Takashi Mizushima, Hirotada Nishie, Hiroyasu Iwasaki, Kaiki Anbe, Takanori Ozeki, Kenta Kachi, Shigeki Fukusada, Yuta Suzuki, Kazuko Watanabe, Hitoshi Sano

Author information

Tadahisa Inoue
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Japan
Fumihiro Okumura
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Japan
Takashi Mizushima
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Japan
Hirotada Nishie
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Japan
Hiroyasu Iwasaki
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Japan
Kaiki Anbe
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Japan
Takanori Ozeki
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Japan
Kenta Kachi
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Japan
Shigeki Fukusada
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Japan
Yuta Suzuki
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Japan
Kazuko Watanabe
Department of Pathology, Gifu Prefectural Tajimi Hospital, Japan
Hitoshi Sano
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Japan

Keywords: IgG4-related cholecystitis, IgG4-related disease, autoimmune pancreatitis, gallbladder neoplasms, adenomyomatosis

JOURNAL OPEN ACCESS

2015 Volume 54 Issue 15 Pages 1869-1874

DOI https://doi.org/10.2169/internalmedicine.54.4383

Details

Abstract

We encountered a case of localized IgG4-cholecystitis mimicking gallbladder cancer with focal/segmental type1 autoimmune pancreatitis (AIP). In this case, we were unable to exclude a diagnosis of gallbladder cancer and thus performed radical cholecystectomy. Type1 AIP is often associated with gallbladder lesions, accompanied by generally diffuse, circumferential thickening of the gallbladder wall. Although localized IgG4-related cholecystitis is extremely rare, differentiating this condition from gallbladder cancer is often very difficult.

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