Nontuberculous Mycobacterial Lung Disease Accompanied by Organizing Pneumonia

Yasuharu Nakahara; Yasutaka Oonishi; Junji Takiguchi; Akie Morimoto; Katsunari Matsuoka; Naoko Imanishi; Takanori Higashino; Rokuro Mimura; Tetsuji Kawamura; Yoshiro Mochiduki

doi:10.2169/internalmedicine.54.3616

CASE REPORTS

Nontuberculous Mycobacterial Lung Disease Accompanied by Organizing Pneumonia

Yasuharu Nakahara, Yasutaka Oonishi, Junji Takiguchi, Akie Morimoto, Katsunari Matsuoka, Naoko Imanishi, Takanori Higashino, Rokuro Mimura, Tetsuji Kawamura, Yoshiro Mochiduki

Author information

Yasuharu Nakahara
Department of Respiratory Medicine, National Hospital Organization Himeji Medical Center, Japan
Yasutaka Oonishi
Department of Respiratory Medicine, National Hospital Organization Himeji Medical Center, Japan
Junji Takiguchi
Department of Respiratory Medicine, Kobe Laborers' Hospital, Japan
Akie Morimoto
Department of Respiratory Medicine, National Hospital Organization Himeji Medical Center, Japan
Katsunari Matsuoka
Department of Respiratory Surgery, National Hospital Organization Himeji Medical Center, Japan
Naoko Imanishi
Department of Respiratory Surgery, National Hospital Organization Himeji Medical Center, Japan
Takanori Higashino
Department of Radiology, National Hospital Organization Himeji Medical Center, Japan
Rokuro Mimura
Department of Pathology, National Hospital Organization Himeji Medical Center, Japan
Tetsuji Kawamura
Department of Respiratory Medicine, National Hospital Organization Himeji Medical Center, Japan
Yoshiro Mochiduki
Department of Respiratory Medicine, National Hospital Organization Himeji Medical Center, Japan

Keywords: nontuberculous mycobacteria, organizing pneumonia, histology, acute, infiltrating shadow, steroid

JOURNAL OPEN ACCESS

2015 Volume 54 Issue 8 Pages 945-951

DOI https://doi.org/10.2169/internalmedicine.54.3616

Details

Abstract

We herein report our experience with patients who had nontuberculous mycobacterial lung disease (NTM disease) accompanied by organizing pneumonia (OP). Out of 98 NTM disease patients who had undergone a biopsy or surgical resection, 11 patients had OP that was revealed histologically. After excluding six patients who had OP-related diseases (idiopathic interstitial pneumonia, rheumatoid arthritis, etc.), the remaining five patients were studied. Two of them (a 73-year-old man and a 66-year-old woman) showed common clinical feature: acute-onset symptoms of cough and fever, infiltrating shadows and dramatic improvement following treatment with a corticosteroid and anti-mycobacterial therapy. Our cases demonstrate that NTM disease is sometimes accompanied by OP histologically, and some such cases show common clinical features.

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