Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Human Parvovirus B19 Infection during the Inactive Stage of Systemic Lupus Erythematosus
Takashiro SUZUKIShinichiro SAITOYasuhiko HlRABAYASHIHideo HARIGAETomonori ISHIITakao KODERAHiroshi FUJIIYasuhiko MUNAKATATakeshi SASAKI
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2003 Volume 42 Issue 6 Pages 538-540

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Abstract

A 42-year-old woman with systemic lupus erythematosus (SLE) had an episode of fever, arthralgia and anemia. In order to treat the suspected activation of SLE, the daily dose of steroid was increased, however, the anemia progressed and pancytopenia developed. Both IgM anti-B19 antibodies to human parvovirus B19 (B19) and B19 DNA were positive, and bone marrow analysis revealed pure red cell aplasia with giant proerythroblasts. High dose γ globulin was administered and the daily dose of steroid was tapered, resulting in the improvement of her condition. B19 infection should be ruled out in cases with reactivation of autoimmune diseases.
(Internal Medicine 42: 538-540, 2003)

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