2000 Volume 46 Issue 6 Pages 280-284
With the intention of examining the effects of dietary protein and oil levels on total cholesterol (T-CHOL) and triacylglycerol (TG) concentrations in the plasma and liver, male Wistar rats, weighing about 170 g, were fed diets containing graded levels of casein and corn oil for 2 wk. At the 5, 20, and 30% levels of dietary corn oil, plasma T-CHOL con-centrations were generally enhanced in proportion to the rise of dietary casein level, but plasma TG contents were scarcely influenced by the level. At the 8 to 3 5% casein levels, plasma T-CHOL and TG concentrations were the highest at the 5% corn oil level, followed in order by the 20 and 30% levels of oil. At the 5 and 20% oil levels, hepatic T CHOL contents were hardly changed at the 8 to 30% casein levels, but enhanced at the 35% casein level. At the 30% oil level, the T-CHOL contents tended to be changed proportionally to casein levels. At all levels of casein, hepatic T-CHOL contents tended to be relatively high at the 30% corn oil, middle at the 20% oil, and low at the 5% one. At each corn oil level, TG contents in the liver tended to be elevated at the 8 to 15% casein levels and highly preserved at the 15 to 25% ones. Then, the raised TG contents declined at the 5 and 20% levels of corn oil and re-mained constant at the 30% oil. At each casein level, the contents of hepatic TG were gener-ally high at the 30% oil level, followed in order by the 20 and 5% oil levels. These results in-dicated that plasma and liver T CHOL concentrations were proportionately enhaaced by the increase in casein level, and plasma TG contents were hardly affected by the level and he-patic TG ones were lowered by relatively lower or higher casein level, and the rise in corn oil level generally reduced plasma T CHOL and TG concentrations, but raised hepatic ones.