A screening for essential cell growth-related genes involved in arsenite toxicity in Saccharomyces cerevisiae

Tsutomu Takahashi; Shohei Satake; Ken-ichiro Hirose; Gi-Wook Hwang; Akira Naganuma

doi:10.2131/jts.36.859

Toxicogenomics/proteomics Report

A screening for essential cell growth-related genes involved in arsenite toxicity in Saccharomyces cerevisiae

Tsutomu Takahashi, Shohei Satake, Ken-ichiro Hirose, Gi-Wook Hwang, Akira Naganuma

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Keywords: Arsenite, Yeast, YPT1, ERG8, RKI1

JOURNAL FREE ACCESS

2011 Volume 36 Issue 6 Pages 859-861

DOI https://doi.org/10.2131/jts.36.859

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Abstract

Genes that are essential for growth in yeast were screened to identify those involved in arsenite sensitivity. We found that the knockdown of YPT1, ERG8, or RKI1 enhanced arsenite sensitivity in yeast.

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