Adhesion of Insect Cells Expressing the Feline Herpesvirus Type 1 Hemagglutinin (gD) to Feline Cell Lines

Ken MAEDA; Mitsuru ONO; Yasushi KAWAGUCHI; Katsunori OKAZAKI; Naoaki YOKOYAMA; Yukinobu TOHYA; Takeshi MIKAMI

doi:10.1292/jvms.59.217

Ken MAEDA, Mitsuru ONO, Yasushi KAWAGUCHI, Katsunori OKAZAKI, Naoaki YOKOYAMA, Yukinobu TOHYA, Takeshi MIKAMI

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Keywords: adhesion, FHV-1 gD, hemagglutinin

JOURNAL FREE ACCESS

1997 Volume 59 Issue 3 Pages 217-219

DOI https://doi.org/10.1292/jvms.59.217

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Abstract

Feline herpesvirus type 1 (FHV-1) gD-expressing Sf9 cells adhered to two feline cell lines, but not to the porcine, bovine, or canine cell lines tested. In addition, this adhesion activity was inhibited by a monoclonal antibody against FHV-1 gD. These results showed that the FHV-1 gD might bind to a specific-molecule(s) on the surface of feline cell lines. We discussed a possible importance of the FHV-1 gD in host cell restriction to FHV-1 infection.

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