Orthogonal frequency division multiple access (OFDMA) is adopted as a multiuser access scheme in recent cellular systems such as long term evolution (LTE) and WiMAX. In those systems, the performance improvement on cell-edge users is crucial to provide high-speed services. We propose a new resource allocation scheme based on multiple input multiple output — orthogonal frequency division multiple access — code division multiplexing (MIMO-OFDMA-CDM) to achieve performance improvements in terms of cell-edge user throughput, bit error rate, and fairness among users. The proposed scheme adopts code division multiplexing for MIMO-OFDMA and a modified proportional fairness algorithm for CDM, which enables the fairness among users and a higher throughput. The performance improvements are clarified by theoretical analysis and simulations.