ACTA HISTOCHEMICA ET CYTOCHEMICA
Online ISSN : 1347-5800
Print ISSN : 0044-5991
ISSN-L : 0044-5991
HISTOCHEMICAL OBSERVATION OF LECTIN-BINDING PATTERNS IN PAGET'S DISEASE
TAKA-AKI NAKAMURASHOJI FUKUSHIMANOBUYUKI ITOYOSHIAKI TAKAIYUKIHIRO TATEMOTOMASAHIKO MORI
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1986 年 19 巻 4 号 p. 451-464

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Histochemical detections of sugar residues with the use of lectin bindings-Con A, PNA, RCA-1, DBA, SBA, UEA-1 and WGA, respectively, were described in Paget cells in both mammary and extramammary Paget's disease. Lectin binding in Paget cells was characterized by existence of stainings to PNA, DBA and SBA lectins, and these findings suggest that higher amounts of galactose, N-acetyl-galactosamine residues were contained. On the contrary, binding to either RCA-1, WGA or UEA-1 was very weak or negative. PAS positive stainability and Con A binding patterns showed parallel relations in Paget cells. Enzyme pre-treatment to Paget cells revealed the enhanced stainings to PNA, DBA and SBA lectins, respectively.

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© the Japan Society of Histochemistry and Cytochemistry
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