Expression of Nitric Oxide Synthases in the Mouse and Human Nasal Mucosa

抄録

An immunohistochemical study was performed to detect the localization of neural-type nitric oxide synthase (nNOS), endothelialtype NOS (eNOS) and inducible-type NOS (iNOS) in the mouse and human nasal mucosa. nNOS-immunoreactive nerve fibers were observed in the subepithelial layer and around the seromucous glands of mice. In these fibers, immunodouble staining revealed colocalization of nNOS and superoxide dismutase. In the human nasal cavity, strong eNOS immunoreactivity and weak iNOS immunoreactivity were found in the columnar epithelium.