The aim of this study is to analyze the relation of visual cognition and informational space through the video of wayfinding experiments which held at two general hospitals with the assumption of first-visit patients. From the series of video pictures, the visual cognition has been classified into "looking in the face" and "looking about". It has been cleared that the visual cognition during the wayfinding behavior in hospital is related to the view from the starting point and its position, to the spatial information like reception desk, void space and open-type stairs, to the size, the number and the position of signs, and to the knowledge of each subjects.