The spatial correlation analysis (SCA) method was proposed in order to analyze urban activities quantitatively. This paper attempts to extend the method of SCA defined in the bi-dimensional Euclidean space to the road-network space. We discuss a method for applying the spatial correlation analysis in the road-network space and illustrate the details of computation methods. As the numerical examples using actual GIS data, the comparison of results from the Euclidean distance and the network distance is shown. Also, we demonstrate some care studies using the variety of computation methods.