The Journal of Showa Hospital
Online ISSN : 1880-151X
Print ISSN : 1880-1528
ISSN-L : 1880-151X
Actin-Myosin System as a nano-machine
Masahiro NakanoKen-ichi MakinoHiroyuki MatsuuraNobuo Noda
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2007 Volume 4 Issue 1 Pages 081-087

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Abstract

Actin-myosin system in muscle is considered as a nano-size machine. In order to understand the principle of the movement, many theories have been proposed. Among these, we propose new model of Stochastic Inclined Rods Model(DS-SIRM). The features are DS-SIRM are as follows. It has many inclined rods stood out from its body and it moves always forward to one direction whenever those rods are independently vibrating. DS-SIRM can convert the thermal noise to the one directional motion by using stochastic resonance and inclined rods in random open fields. Our aim in this paper is to show directly that the our new improved SIRM model (DS-SIRM), which is proposed in this paper, does agree with the recent experimental data by Yanagida et al. Moreovere, we attempt to explain a role of ATP hydrolysis and a energy consumption.. On the basis of these findings, we discuss on the control and management of the motion in action-myosin system. We discuss first the structure and mechanism of the movement, then show the importance of the manage-ment system of the motion, Finally We estimated concretely the physical characteristics of DS-SIRM as a con-ceptual model of actin-myosin system. Especially the mass, and spring constants and its used energy.

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© 2007 by Akane Medical Corporation Akatsuki Social Welfare Corporation
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