Separation and Determination of Diastereomers of λ-Cyhalothrin by Normal Phase-Liquid Chromatography Using a CN Column

Abstract

A simple and rapid normal-phase liquid-chromatographic method for the separation and determination of diastereomers of λ-cyhalothrin using a CN column and detection at UV-230 nm has been developed. This method has the advantage of totally resolving each of the diastereomers from impurities, such as meta-phenoxy benzaldehyde, cyhalothric acid and cyhalothric acid chloride, of technical and formulated materials, allowing one to monitor the low-temperature conversion of diastereomers of λ-cyhalothrin for process development.