2015 Volume 31 Issue 4 Pages 331-335
Herein, we report on a new 19F MRI probe for the detection and imaging of H2O2. Our designed 2-fluorophenylboronic acid-based 19F probe promptly reacted with H2O2 to produce 2-fluorophenol via boronic acid oxidation. The accompanying 19F chemical-shift change reached 31 ppm under our experimental conditions. Such a large chemical-shift change allowed for the imaging of H2O2 by 19F chemical-shift-selective MRI.