Analytical Sciences
Online ISSN : 1348-2246
Print ISSN : 0910-6340
ISSN-L : 0910-6340
Notes
Phenylboronic Acid-based 19F MRI Probe for the Detection and Imaging of Hydrogen Peroxide Utilizing Its Large Chemical-Shift Change
Hiroshi NONAKAQi ANFuminori SUGIHARATomohiro DOURAAkira TSUCHIYAYoshichika YOSHIOKAShinsuke SANDO
Author information
JOURNALS FREE ACCESS

2015 Volume 31 Issue 4 Pages 331-335

Details
Abstract

Herein, we report on a new 19F MRI probe for the detection and imaging of H2O2. Our designed 2-fluorophenylboronic acid-based 19F probe promptly reacted with H2O2 to produce 2-fluorophenol via boronic acid oxidation. The accompanying 19F chemical-shift change reached 31 ppm under our experimental conditions. Such a large chemical-shift change allowed for the imaging of H2O2 by 19F chemical-shift-selective MRI.

  Fullsize Image
Information related to the author
© 2015 by The Japan Society for Analytical Chemistry
Previous article Next article
feedback
Top