Analytical Sciences
Online ISSN : 1348-2246
Print ISSN : 0910-6340
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Analysis of Long-term Morphological Changes of Micro-patterned Molecules and Cells on PDMS and Glass Surfaces
Shun-ichi FUNANONobuyuki TANAKAYo TANAKA
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Volume 33 (2017) Issue 6 Pages 723-725

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Abstract

We demonstrated that our previously developed gas-phase fluoroalkylsilane patterning method was applicable to polydimethylsiloxane (PDMS) and we compared the stability of patterned proteins and cultured cells between PDMS and glass surfaces. The shapes of the protein patterns were stable on both glass and PDMS surfaces for more than 1 week. The cell patterns were stable on glass surfaces for 1 week, while those on PDMS collapsed within a few days. These results indicated that our method was applicable to PDMS, although, compared with glass, PDMS has an unsolved issue for its application to long-term patterning of cells.

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© 2017 by The Japan Society for Analytical Chemistry
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