Analytical Sciences
Online ISSN : 1348-2246
Print ISSN : 0910-6340
ISSN-L : 0910-6340
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A RuO2 Nanosheet as a Novel Quencher-free Platform for the Detection of Nucleic Acids in a Homogeneous Solution
Yusuke KITAMURATakaaki TANIGUCHIMiwako TSUTSUMILeanddas NURDIWIJAYANTOTomoya MATSUOYousuke KATSUDAToshihiro IHARA
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2020 Volume 36 Issue 4 Pages 397-400

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Abstract

A fluorescent dye-labeled DNA probe was adsorbed and quenched on the monolayer of RuO2 nanosheets. Significant fluorescent recovery was observed upon the addition of complementary DNA due to desorption of the probe from the surface of the RuO2 nanosheet through duplex formation. The efficiency of fluorescence recovery was higher than that for graphene oxide, which was known as a quencher-free platform for the detection of nucleic acids in a homogeneous solution.

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© 2020 by The Japan Society for Analytical Chemistry
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