1986 Volume 2 Issue 6 Pages 577-580
Volatile N-nitrosamines (NAs) in rubber nipples for baby bottles were determined by gas chromatography (GC) using a thermal energy analyzer (TEA). Rubber nipple samples were cut into pieces, and NAs were extracted with dichloromethane under ultrasonic irradiation. The samples were cleaned by liquid-liquid partition. The detection limits of NAs in samples (S/N=2) were 0.5ppb for N-nitrosodimethylamine (NDMA), 1ppb for N-nitrosodiethylamine (NDEA), 4ppb for N-nitroso-n-butylamine (NDBA), 3ppb for N-nitrosopiperidine (NPIP) and 4ppb for N-nitrosomorphorine (NMOR). The recoveries and the relative standard deviation of NAs added to samples were 95.3% and 3.1% for NDMA, 98.7% and 2.1% for NDEA, 89.5% and 2.8% for NDBA, 93.7% and 2.9% for NPIP, and 95.4% and 3.0% for NMOR.
