Analytical Sciences
Online ISSN : 1348-2246
Print ISSN : 0910-6340
ISSN-L : 0910-6340
Determination of Drugs in Human Serum by Liquid Chromatography/Atmospheric Pressure Ionization Mass Spectrometry
Minoru SAKAIRI, Hideki KAMBARA
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Keywords: Liquid chromatography, atmospheric pressure ionization mass spectrometry, drug monitoring, human serum
JOURNAL FREE ACCESS

1988 Volume 4 Issue 2 Pages 199-201

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Abstract

A rapid and highly sensitive method to determine drugs in human serum by liquid chromatography/atmospheric pressure ionization mass spectrometry (LC/API-MS) is reported. This method has wide applicability and high sensitivity, with detection limits ranging from ng/ml to μg/ml. Experimental results demonstrate that the LC/API-MS is very promising for determination of drugs in human serum.

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© The Japan Society for Analytical Chemistry
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