Development of Macroporous Polymer Packings for Aqueous High Flow Rate Liquid Chromatography. Approach on the Viewpoint of Materials Chemistry

Abstract

Gel production methods have recently been improved, and a systematic search for packing materials has led to the creation of various hard particles from hydrophilic condensation polymers, making it possible for aqueous gel permeation chromatographic separation to occur at higher flow rates. In the present review, we explain the production methods, efficiency, and applications of hydrophilic packings developed due to this improvement in packing materials, while especially emphasizing their hardness.