The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ORALLY ACTIVE CEPHALOGLYCIN ESTERS
E. BINDERUPW. O. GODTFREDSENK. ROHOLT
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1971 Volume 24 Issue 11 Pages 767-773

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Abstract

The preparation of the acetoxymethyl and pivaloyloxymethyl esters of cephaloglycin is described. These esters are well absorbed from the gastrointestinal tract and after the absorption are cleaved enzymatically with the liberation of cephaloglycin. As a result high blood- and tissue-levels of the latter are attained.

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© Japan Antibiotics Research Association
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