The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
PAPULACANDINS, A NEW FAMILY OF ANTIBIOTICS WITH ANTIFUNGAL ACTIVITY
I. FERMENTATION, ISOLATION, CHEMICAL AND BIOLOGICAL CHARACTERIZATION OF PAPULACANDINS A, B, C, D AND E
P. TRAXLERJ. GRUNERJ. A. L. AUDEN
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1977 Volume 30 Issue 4 Pages 289-296

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Abstract

Papulacandin, a new antibiotic complex, active against Candida albicans and several other yeasts, was isolated from a strain of Papularia sphaerosperma. The fermentation, isolation, physico-chemical properties and biological activity of the five structurally related papulacandins A, B, C, D and E are reported. Papulacandin B, the main component, was assigned the formula of C47H64O17.

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© Japan Antibiotics Research Association
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