STUDIES ON BACTERIAL CELL WALL INHIBITORS VII. AZUREOMYCINS A AND B, NEW ANTIBIOTICS PRODUCED BY <i>PSEUDONOCARDIA AZUREA</i> NOV. SP. TAXONOMY OF THE PRODUCING ORGANISM, ISOLATION, CHARACTERIZATION AND BIOLOGICAL PROPERTIES

SATOSHI OMURA; HARUO TANAKA; YOSHITAKE TANAKA; PRISKA SPIRI-NAKAGAWA; RUIKO OIWA; YOKO TAKAHASHI; KYOKO MATSUYAMA; YUZURU IWAI

doi:10.7164/antibiotics.32.985

STUDIES ON BACTERIAL CELL WALL INHIBITORS VII. AZUREOMYCINS A AND B, NEW ANTIBIOTICS PRODUCED

BY PSEUDONOCARDIA AZUREA NOV. SP. TAXONOMY OF THE PRODUCING ORGANISM, ISOLATION, CHARACTERIZATION AND BIOLOGICAL PROPERTIES

SATOSHI OMURA, HARUO TANAKA, YOSHITAKE TANAKA, PRISKA SPIRI-NAKAGAWA, RUIKO OIWA, YOKO TAKAHASHI, KYOKO MATSUYAMA, YUZURU IWAI

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JOURNAL FREE ACCESS

1979 Volume 32 Issue 10 Pages 985-994

DOI https://doi.org/10.7164/antibiotics.32.985

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Abstract

Two new basic water-soluble antibiotics, azureomycins A and B, were isolated from the culture broth of an actinomycete, strain AM-3696, designated as Pseudonocardia azurea nov. sp. The antibiotics exhibit moderate antimicrobial activities against Gram-positive bacteria including penicillin-resistant Staphylococcus, Mycobacterium and Clostridium. They inhibit the synthesis of bacterial cell wall peptidoglycan.

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