CHLORAMPHENICOL RESISTANCE OF THREE DIFFERENT FLAVOBACTERIA
1979 Volume 32 Issue 12 Pages 1293-1302
Details
1979 Volume 32 Issue 12 Pages 1293-1302
The chloramphenicol resistance of some flavobacteria was investigated comparatively.
This resistance can be explained either by acetylation of chloramphenicol to O-acetylchloramphenicol
via constitutively formed acetyltransferases, followed by cometabolic degradation
(strain CB 60), or by limited uptake and total degradation (strain CB 6) by inducible
enzymes or by other mechanisms (F. devorans). The mechanisms of resistance, CM-acetylation,
CM-degradation and limited uptake are discussed.
